BDBM25878 5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one::CHEMBL13280::Flunitrazepam::[3H]Rohypnol::[3H]flunitrazepam

SMILES CN1c2ccc(cc2C(=NCC1=O)c1ccccc1F)[N+]([O-])=O

InChI Key InChIKey=PPTYJKAXVCCBDU-UHFFFAOYSA-N

Data  36 KI  5 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 25878   

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
University of Cagliari

Curated by PDSP Ki Database
LigandPNGBDBM25878(5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H...)
Affinity DataKi:  1.37nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
University of Cagliari

Curated by PDSP Ki Database
LigandPNGBDBM25878(5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H...)
Affinity DataKi:  1.52nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM25878(5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H...)
Affinity DataKi:  5.20nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM25878(5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H...)
Affinity DataKi:  11.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
University of Cagliari

Curated by PDSP Ki Database
LigandPNGBDBM25878(5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H...)
Affinity DataKi:  14.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
University of Cagliari

Curated by PDSP Ki Database
LigandPNGBDBM25878(5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H...)
Affinity DataKi:  29nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
University of Cagliari

Curated by PDSP Ki Database
LigandPNGBDBM25878(5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H...)
Affinity DataKi:  40.4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
University of Cagliari

Curated by PDSP Ki Database
LigandPNGBDBM25878(5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H...)
Affinity DataKi:  3.14E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
University of Cagliari

Curated by PDSP Ki Database
LigandPNGBDBM25878(5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H...)
Affinity DataKi:  3.45E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM25878(5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H...)
Affinity DataKd:  4.5nMAssay Description:Binding affinity to GABAA alpha-1-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed